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These organelles are highly dynamic structures, ceaselessly moving, and in reality, their size and even their very existence can change within a few tens of minutes as a function of learning ( Figure 2 )
Other outcomes and changes could have been used to align with other published ITCs in the literature
N Engl J Med 355:24272443 Patane G, Piro S, Rabuazzo AM, Anello M, Vigneri R, Purrello F (2000) Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells
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